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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRAP1
All Species:
15.76
Human Site:
Y47
Identified Species:
34.67
UniProt:
P42345
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42345
NP_004949.1
2549
288892
Y47
A
A
K
E
L
Q
H
Y
V
T
M
E
L
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535407
2550
288910
Y47
A
A
K
E
L
Q
H
Y
V
T
M
E
L
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN9
2549
288718
Y47
A
A
K
E
L
Q
H
Y
V
T
M
E
L
R
E
Rat
Rattus norvegicus
P42346
2549
288776
Y47
A
A
K
E
L
Q
H
Y
V
T
M
E
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510680
2493
282092
A47
S
A
E
R
L
L
R
A
E
H
R
T
E
R
L
Chicken
Gallus gallus
XP_417614
2463
280042
S49
Y
L
R
N
L
L
P
S
N
D
P
V
V
M
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070679
2515
286136
F49
S
Q
D
E
A
T
T
F
Y
D
E
L
N
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK45
2470
281015
F52
L
A
Q
F
F
D
E
F
D
H
H
I
F
T
M
Honey Bee
Apis mellifera
XP_625130
2442
278856
F47
S
Q
E
E
I
T
A
F
M
D
E
F
N
H
H
Nematode Worm
Caenorhab. elegans
Q95Q95
2697
306510
P85
R
S
E
L
K
D
E
P
N
T
F
S
D
A
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32600
2474
281549
S114
E
L
S
T
T
L
T
S
L
A
R
E
V
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.4
N.A.
98.9
98.9
N.A.
88.8
93.7
N.A.
89.8
N.A.
54
62
34.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99.2
99.2
N.A.
91.2
95.4
N.A.
94.5
N.A.
69.8
75.7
53.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
20
13.3
N.A.
6.6
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
33.3
26.6
N.A.
20
N.A.
20
40
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
55
0
0
10
0
10
10
0
10
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
19
0
0
10
28
0
0
10
0
0
% D
% Glu:
10
0
28
55
0
0
19
0
10
0
19
46
10
0
46
% E
% Phe:
0
0
0
10
10
0
0
28
0
0
10
10
10
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
37
0
0
19
10
0
0
19
19
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
37
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
19
0
10
55
28
0
0
10
0
0
10
37
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
37
0
0
10
10
% M
% Asn:
0
0
0
10
0
0
0
0
19
0
0
0
19
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% P
% Gln:
0
19
10
0
0
37
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
10
0
0
10
0
0
0
19
0
0
46
0
% R
% Ser:
28
10
10
0
0
0
0
19
0
0
0
10
0
10
0
% S
% Thr:
0
0
0
10
10
19
19
0
0
46
0
10
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
37
0
0
10
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
37
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _